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How Scientists Use Lasers to Measure Farts: A Journey Down a Research Rabbit Hole

One of my favorite aspects of diving deep into any topic is uncovering the fascinating tangential insights that emerge along the way. As part of researching healthier eating habits, I have been listening to the latest season of the "Try This" podcast from the Washington Post that mentioned scientists using lasers to measure farts as part of microbiome research. I couldn't let that little tidbit of information go unearthed! What started as a simple curiosity about digestive health led me down an incredible rabbit hole into the sophisticated world of laser spectroscopy and intestinal gas analysis. Sometimes the most interesting knowledge comes from these unexpected detours, so I wanted to share this particular gem of scientific ingenuity.

The Science Behind Laser-Measured Flatulence

Scientists use lasers to measure intestinal gas through a sophisticated technique called tunable diode laser absorption spectroscopy (TDLAS), which has revolutionized the study of gastrointestinal health and the microbiome. This technology works by emitting laser light at specific wavelengths that correspond to the absorption lines of particular gas molecules like hydrogen, methane, carbon dioxide, and ammonia found in breath and intestinal gas12. When these gases absorb the laser light at their characteristic wavelengths, scientists can precisely measure their concentrations by analyzing how much light is absorbed3. This method is incredibly sensitive, capable of detecting gas concentrations at parts-per-million or even parts-per-billion levels, making it ideal for measuring the tiny amounts of gases produced by bacterial fermentation in the gut.

The laser measurement technology has found two key applications in studying intestinal gas and the microbiome. First, it's used in hydrogen and methane breath tests to diagnose conditions like small intestinal bacterial overgrowth (SIBO), lactose intolerance, and other digestive disorders by measuring gases that bacteria produce when fermenting undigested carbohydrates45. These gases are absorbed into the bloodstream from the intestines and expelled through the lungs, where laser spectroscopy can detect them with remarkable precision6. Second, researchers are using this technology to study how the gut microbiome responds to different foods and treatments, as recent studies have shown that photobiomodulation (using red and near-infrared laser light) can actually alter the composition of gut bacteria and significantly change the microbial diversity of the microbiome78. This emerging field, termed "photobiomics," suggests that laser technology isn't just measuring intestinal gas—it may also be influencing the very bacteria that produce it.


References

Footnotes

  1. Near-infrared tunable diode laser absorption spectroscopy-based determination of carbon dioxide in human exhaled breath. PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC6865105/

  2. Human breath trace gas content study by tunable diode laser spectroscopy technique. ScienceDirect. https://www.sciencedirect.com/science/article/abs/pii/1350449595000976

  3. Diode Laser Absorption Spectroscopy - an overview. ScienceDirect Topics. https://www.sciencedirect.com/topics/engineering/diode-laser-absorption-spectroscopy

  4. Hydrogen Breath Test: What Is It, How To Prep & Results. Cleveland Clinic. https://my.clevelandclinic.org/health/diagnostics/12360-hydrogen-breath-test

  5. Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus. PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC5418558/

  6. Hydrogen breath test. Wikipedia. https://en.wikipedia.org/wiki/Hydrogen_breath_test

  7. "Photobiomics": Can Light, Including Photobiomodulation, Alter the Microbiome? Photobiomodulation, Photomedicine, and Laser Surgery. https://www.liebertpub.com/doi/full/10.1089/photob.2019.4628

  8. "Photobiomics": Can Light, Including Photobiomodulation, Alter the Microbiome? PMC. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859693/